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. 2021 May 3;9(5):452. doi: 10.3390/vaccines9050452

Table 2.

Nucleotide modifications used in the synthesis of modified RNA.

Modification M0 M1 M2 M3
Base composition A, G(+ARCA), C, U A, G, C, Ψ 100% A, G(+ARCA), C, Ψ 100% A, G(+ARCA), C, Ψ 50%
Modification M4 M5 M6 M7
Base composition A, G(+ARCA), C, Ψ 50%, m5C 50% A, G(+ARCA), C, Ψ 50%, m5C 50%, m6A 20% A, G (+ARCA), C, Ψ 100%, m6A 20% A, G, C, Ψ 100% + cap(1)