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. 2021 May 4;11(5):416. doi: 10.3390/life11050416

Figure 3.

Figure 3

Nodule on the right little finger of a 30-year-old sheep farmer infected with ORFV. (A) Targetoid nodule with a necrotic center, a white ring, and peripheral erythema. (B) Microscopical appearance of the skin of the ORF-infected man, characterized by marked acanthosis and hyperkeratosis. Hematoxylin and eosin staining (H&E). Original magnification 50×. Scale bar = 250 µm. (C) In the dermis, vascular proliferation with granulocytic and eosinophilic infiltration. Hematoxylin and eosin staining (H&E). Original magnification 400×. Scale bar = 100 µm.