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. 2021 May 4;13(5):828. doi: 10.3390/v13050828

Table 3.

Natural compounds and their antiviral targets against Papillomaviruses.

Natural Source Compound Papillomaviruses Target Reference
Curcuma longa L. Curcumin HPV-16
HPV-18
Downregulating expression of
oncogenes E6 and E7
[39]
Ficus carica Latex HPV-16 [41]
C. longa, A. indica, E. officinalis, A. vera Basant HPV-16 Prevents the entry of HPV 16 in Hela cells [40]
Green tea Epigallocatechin-3-gallate (EGCG) HPV-16 Promoting apoptosis and inhibiting cellular transcriptional factors [43]
Pinellia pedatisecta Rhizome extract HPV-16
HPV-18
[44]
Cudrania tricuspidata Stem extract HPV-16 [45]
Curcuma longa L. Curcumin HPV-18
HPV-16
[46]
Bryophyllum pinnata Leaves extract HPV-18 [47]
Phyllanthus emblica Crude extract HPV-16
HPV-18
[48]
Kaempferia parviflora Ethanolic extract HPV-16 [49]