. 2021 May 4;13(5):828. doi: 10.3390/v13050828

Table 6.

Natural products against Influenza viruses.

Natural Source	Compound	Influenza Viruses	Target	CC₅₀	EC₅₀-IC₅₀	SI	Reference
Litchi chinensis	Oligonol	H3N2	Blocking (ROS)-dependent ERK phosphorilation				[83]
Green tea	Catechins	H1N1	Inhibiting RNA polymerase				[84]
Aglaia	Silvestrol	H1N1	Inhibitors of the cellular factor eEIF4A				[85]
Mycale hentscheli	Pateamine A	H1N1 H3N2	Inhibitors of the cellular factor eEIF4A				[85]
Curcuma longa L.	Curcumin	H1N1 H6N1	Haemagglutinin inhibitors	43 µM	0.47 µM	92.5	[86]
Cistus incanus	Polyphenol rich extract	A549			50 μg/mL		[87]
Punica granatum	Punicalagin	H3N2					[89]
Green tea	Epigallocatechin gallate	H1N1					[90]
Blak tea	Theaflavin digallate	H1N1					[90]

CC₅₀: Half maximal cytotoxic concentration; EC₅₀-IC₅₀: Half maximal inhibitory concentration; SI: Selectivity index = CC₅₀/IC₅₀.