Table 5:
Proportion of times each covariate is selected across the four models fitted on simulated survival times from a Weibull PH model. The column “Coefficient” denotes the true coefficient value used in the simulations, multiplied by the corresponding covariate’s standard deviation. The column “× Time” is the proportion of times the HARE non-PH model selected an interaction between the covariate and time.
| Covariates | Coefficient | PH | Penalized PH | HARE PH | HARE non-PH | × Time |
|---|---|---|---|---|---|---|
| ZDV + ddI | −0.323 | 1.000 | 0.986 | 0.992 | 0.992 | 0.008 |
| ZDV + ZAL | −0.299 | 1.000 | 0.978 | 0.982 | 0.980 | 0.004 |
| ddI | −0.237 | 0.992 | 0.786 | 0.966 | 0.962 | 0.006 |
| Age | −0.158 | 0.938 | 0.968 | 0.826 | 0.826 | 0.014 |
| Wtkg | 0.00 | 0.046 | 0.178 | 0.004 | 0.004 | 0.000 |
| Hemo | 0.00 | 0.030 | 0.210 | 0.010 | 0.010 | 0.002 |
| Drugs | 0.00 | 0.072 | 0.260 | 0.012 | 0.012 | 0.000 |
| Karnof | 0.00 | 0.056 | 0.190 | 0.008 | 0.008 | 0.000 |
| Oprior | 0.00 | 0.044 | 0.186 | 0.008 | 0.008 | 0.000 |
| Preanti | 0.217 | 1.000 | 1.000 | 0.986 | 0.986 | 0.006 |
| Race | 0.00 | 0.052 | 0.202 | 0.010 | 0.010 | 0.000 |
| Gender | 0.00 | 0.076 | 0.224 | 0.008 | 0.008 | 0.000 |
| Symptom | 0.164 | 0.962 | 0.972 | 0.866 | 0.868 | 0.000 |
| Offtrt | −0.420 | 1.000 | 1.000 | 1.000 | 1.000 | 0.008 |
| CD40 | 4.586 | 1.000 | 1.000 | 1.000 | 1.000 | 0.028 |
| CD80 | 0.222 | 1.000 | 1.000 | 0.984 | 0.984 | 0.014 |