Table 1.

Potential cross-reactive epitopes between alpha-synuclein proteins and yeast proteins.

Yeast Protein	Yeast Sequence	Mapped Start To End	Alpha-Synuclein Sequence	ID (%)
Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO	MDIFSQ-LSRAK	45–55	MDVFMKGLSKAK	58
Proteasome Activator Complex	KATNGVVIATE	19–29	KAKEGVVAAAE *	64
Structure of the ribosomal 80S-eEF2-sordarin complex	FMKKLRAAK---LAAPE	10–23	FMKGLSKAKEGVVAAAE *	53
Crystal Structure of the S. cerevisiae glucokinase, Glk1	MEKGLAPPKEG	43–53	M-KGLSKAKEG	64
Solution structure of the oxidized form of the Yap1 redox domain	MAKAKCSERGVVINAE	60–75	LSKAK--E-GVVAAAE	56
Cryo-EM Structure of the RIX1-REA1 Pre-60S Particle	KG-SKAK-GVNMAA	471–482	KGLSKAKEGV-VAA	71
Crystal structure of yeast elongation factor 2 in complex with sordarin	SKAGEIVLAA	813–822	SKAKEGVVAA *	70
Solution structure of the SBDbeta domain of yeast Ssa1	KGRLSKEDIEKMVAEAE	123–139	KG-LSKAK-EGVVAAAE	59
Crystal structure of the RNA recognition motif of yeast eIF3b residues 76–161	EATGKTK-GFLFV	48–59	EAAGKTKEGVLYV *	69
Structure of the ribosomal 80S-eEF2-sordarin complex from yeast	TKEAAAVAEGKSKQ	9–22	TKQGVAEAAGKTKE *	50
Crystal structure of a Prp8 C-terminal fragment	KQNDEEAAGASTVMKTK	276–292	KQGVAEAAG-----KTK *	53
Crystal Structures of Yeast Transketolase In Complex with Analogs of Thiamin Diphosphate	TPEGVAERAQKT	650–661	TKQGVAEAAGKT *	67
Crystal Structure of Yeast Aspartyl-Trna Synthetase Complexed with Trna Asp	KEGI-EMLRAAGK	336–347	KQGVAE---AAGK	54
A Gated Channel into The Proteasome Core Particle	TKEGVVLGV----EK	42–52	TKEGVVHGVATVAEK *	67
Structure of The Yeast Cytochrome Bc1 Complex Co-Crystallized with An Antibody Fv-Fragment	GSRYATKDGVAH	22–33	GSK—TKEGVVH *	58
Electron cryomicroscopy structure of S. cerevisiae FAS in the Apo state	SKTIKD-LVGGKSTV	169–182	SKT-KEGVVHGVATV *	53
Structure of the Ndi1 protein in complex with the competitive inhibitor, stigmatellin	VHLRTAVAKVEEK	271–283	VH---GVATVAEK *	54
Cryo-EM Structure of the Exocyst Complex	QVNSIGGVVVT	781–791	QVTNVGGAVVT	64
Arx1 pre-60S particle	NVGGALRVPG--AISEK	44–58	NVGGAV-VTGVTAVAQK	53
Crystallographic snapshots of eukaryotic dimethylallyltransferase acting on tRNA	IAGTTG-VGKSQL	7–18	IAAATGFVKKDQL *	62
Crystal structure of yeast aminopeptidase 1 (Ape1)	TAEGYGRIAVA	104–114	TVEGAGSIAAA *	64
Yeast RNA polymerase III initial transcribing complex	DNEDNE-GSEE-----EPE	579–591	DNEAYEMPSEEGYQDYEPE *	53

* This match occurred in more than one section of the target sequence. Not all of the instances of identification and similarity are shown due to the overwhelming number of occurrences.