Table 4.
Potential cross-reactive epitopes between alpha-synuclein proteins and wheat germ agglutinin.
| Wheat Germ Agglutinin Protein | Wheat Germ Agglutinin Sequence |
Mapped Start to End | Alpha-Synuclein Sequence |
ID (%) |
|---|---|---|---|---|
| Chain A, Glutaredoxin | LAKAKE-IVASA | 53–63 | LSKAKEGVVAAA | 67 |
| Chain Y, 60s Ribosomal Protein L24 | KAKGKFTAEDV-AAA | 129–142 | KAK-----EGVVAAA | 53 |
| Chain I, 60s Ribosomal Protein L16 | DVGMK-----KKGV | 35–43 | DVFMKGLSKAKEGV | 50 |
| Chain F, 60s Ribosomal Protein L30 | KQKVAAEKIKAAENTK--VIY | 29–47 | KQGV-AE---AAGKTKEGVLY | 52 |
| Chain u, 60s Ribosomal Protein P1 | GGAAAAEEKKE | 80–90 | GVAEAAGKTKE | 55 |
| Chain A, Xylanase Inhibitor Protein I | VHPKNVYYGVAPVAQK | 231–246 | VH------GVATVAEK | 50 |
| Chain H, 60s Ribosomal Protein L6 | EGVTVQ-VAAKVVTV | 14–27 | EGV-VHGVA----TV | 53 |
| Chain M, 40s Ribosomal Protein S12e | VHLV-TVPSAKT | 114–124 | VHGVATV-AEKT | 58 |
| Chain X, Xylanase Inhibitor | GSKPVSKVNV--GV | 109–120 | GSK—TKEGVVHGV * | 50 |
| Chain A, Eukaryotic Translation Initiation Factor 4e-1 | GAVV----SVRQK | 114–122 | GAVVTGVTAVAQK | 54 |
| Chain A, Ribulose bisphosphate carboxylase large chain | EEAGAAVAAESSTG | 51–64 | EGAGS-IAA--ATG | 50 |
| Chain J, 60s Ribosomal Protein L5 | GIQEHIDLGMKYDP | 107–120 | GILE--D--MPVDP | 50 |
* This match occurred in more than one section of the target sequence. Not all of the instances of identification and similarity are shown due to the overwhelming number of occurrences.