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CONSORT study design. Eligibility was assessed in 441 CKD patients, and 41 healthy volunteers with 23 CKD patients and 27 healthy volunteers enrolled and randomized in the Synbiotic (S) (n = 13 CKD, n = 12 healthy) and Placebo (P) arm (n = 10 CKD, n = 15 healthy). No CKD patient dropped out, while in the healthy volunteer group, three subjects dropped out, two allocated in the S-arm and one in the P-arm.
