Table 2.
Baseline characteristics of the enrolled population of healthy volunteers.
| P | S | Difference at Baseline (p Value) | |
|---|---|---|---|
| Gender | 4 M, 10 F | 5 M, 5 F | - |
| Age | 42.7 ± 2.7 | 41.6 ± 3.0 | 0.8 |
| BMI | 23.5 ± 0.8 | 26 ± 1.6 | 0.1 |
| Serum creatinine mg/dl | 0.79 ± 0.0 | 0.83 ± 0.0 | 0.5 |
| sys BP (mmHg) | 109.2 ± 2.6 | 115.6 ± 3.5 | 0.2 |
| dia BP (mmHg) | 68.8 ± 2.1 | 78.3 ± 2.2 | 0.01 |
| Serum albumin (g/dL) | 4.2 ± 0.1 | 4.1 ± 0.1 | 0.4 |
| Azotemia (mg/dL) | 32.6 ± 1.1 | 36.4 ± 3.1 | 0.2 |
| BUN (mg/dL) | 15.3 ± 0.3 | 17.0 ± 1.4 | 0.2 |
| Blood glucose (mg/dL) | 71.5 ± 2.5 | 75.2 ± 3.2 | 0.4 |
| HbA1c % | 33.3 ± 1.3 | 34.6 ± 1.0 | 0.5 |
| Serum tryglicerides (mg/dL) | 65.8 ± 6.8 | 91 ± 9.8 | 0.04 |
| HDL cholesterol (mg/dL) | 72.7 ± 4.1 | 72.2 ± 7.4 | 1.0 |
| LDL cholesterol (mg/dL) | 100.2 ± 5.1 | 113.4 ± 8.5 | 0.2 |
| Total cholesterol mg/dL | 186.8 ± 6.3 | 204 ± 10.0 | 0.1 |
| Serum calcium (mg/dL) | 9.3 ± 0.1 | 9.2 ± 0.1 | 0.1 |
| Serum phosphorus (mg/dL) | 3.4 ± 0.1 | 3.2 ± 0.2 | 0.4 |
| Serum potassium (mEq/L) | 4.1 ± 0.1 | 4.1 ± 0.1 | 1.0 |
| CaxP (mg2/dL2) | 31.9 ± 1.4 | 29.6 ± 1.9 | 0.3 |
| Total serum proteins (g/dL) | 7.5 ± 0.2 | 7.4 ± 0.1 | 0.8 |
| CRP (mg/L) | 2.9 ± 0.0 | 4.2 ± 1.3 | 0.3 |
| Urinary creatinine (mg/dL) | 103.2 ± 11.0 | 157.1 ± 29.4 | 0.1 |
| Proteinuria (mg/dL) | 89 ± 10.6 | 125.9 ± 17.9 | 0.1 |
Data are expressed as mean ± SEM, differences tested by Mann–-Whitney test. Abbreviations: BMI (body mass index), BP (blood pressure), HbA1c (glycated hemoglobin), HDL (high-density lipoprotein), LDL (low-density lipoprotein), CaxP (calcium-phosphorus product), CRP (C-reactive protein).