Table 8.

GSRS scores in the CKD group (13 S and 10 P).

		T0	T2	T3	p-Value Between Time Points
GSRS 6	P	2.40 ± 0.41	2.20 ± 0.51	2.00 ± 0.32	-
	S	2.38 ± 0.34	2.08 ± 0.41	1.46 ± 0.23 *	0.04
GSRS 13	P	2.20 ± 0.76	1.40 ± 0.38	1.40 ± 0.38	-
	S	2.23 ± 0.27	1.15 ± 0.15 *	1.31 ± 0.20 *	<0.004
Abdominal pain	P	4.00 ± 0.58	4.40 ± 0.75	3.40 ± 0.25	-
	S	4.85 ± 0.51	3.54 ± 0.28 *	3.62 ± 0.34	0.03 *
Constipation syndrome	P	5.00 ± 0.69	4.00 ± 0.58	4.40 ± 0.64	-
	S	6.08 ± 0.80	3.77 ± 0.41*	4.23 ± 0.71	0.02 *

Only GSRS items and domains showing statistically significant changes after the treatment (items 4, 6 and 13, abdominal pain, indigestion syndrome and constipation syndrome) are shown. * p < 0.05 vs. T0. Data are expressed as mean ± SEM, differences tested by Kruskal–Wallis multiple-comparison z-value test.