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. 2021 May 5;10(5):408. doi: 10.3390/biology10050408

Figure 3.

Figure 3

Hepatic urea and albumin expression as a function of gel stiffness in the monoculture and coculture. (A) Quantification of urea synthesis by primary hepatocytes on soft (2 kPa), stiff (55 kPa), and TCPS substrates; (B) quantification of albumin synthesis primary hepatocytes cultured on soft (2 kPa), stiff (55 kPa), and TCPS substrates. Error bars indicate standard deviation of the mean for n = 5 samples. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.