Figure 6.

Intermolecular docking-guided presumptive interaction of GPcl residues with HuscFvs. (A–C) Ball-and-stick models showing presumptive interaction of HuscFv4 (A), HuscFv11 (B), and HuscFv14 (C), with residues of trimeric GPcl or monomeric GPcl as determined by computerized homology modeling and intermolecular docking, as described in Figure 5B. The amino acid backbones and side chains of GPcl (purple) and HuscFvs (green) are shown. GP1, GP2, and RBS of the GPcl and contact surface areas between the HuscFvs and the GPcl are colored as described in Figure 5B. Tables at the right of each respective figures indicate the detailed residues and domains of GPcl and HuscFvs that formed the contact interface.