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Effect of pH on cell death. A549 cells were incubated with increasing concentrations of (A) free (T21) or encapsulated T21 (NC-T21), (B) cisplatin, and (C) staurosporine at pH 6.8 and 7.8 for 24 h. Dead cells were counted by trypan blue staining, average ± SD of 3 independent experiments is represented. ** p > 0.01, **** p > 0.0001.
