Table 1.
Selected plant extracts from different species with identified phenolic compounds and their in vitro effect on dermal fibroblast cells and ROS production.
Name of the Families | Name of the Species (Common Names) |
Part of the Plant | Type of Extract (Concentrations) |
Identified Bioactive | Cell Lines | Mechanisms of Action | Ref. |
---|---|---|---|---|---|---|---|
Annonaceae |
Annona muricata L. (soursop) |
leaves | aqueous (12.5 to 200 µg/mL) |
quercetin 3-glucoside, rutin, chlorogenic acid, catechin, and gallic acid | L929 fibroblasts exposed to 750 µmol/L H2O2 | Reduced ROS production | [76] |
Onagraceae |
Fuchsia magellanica Lam. (hardy fuchsia) |
leaves | aqueous/ethanolic (1000 µg/mL) |
various phenolic acid, flavonoid, and anthocyanin derivatives |
3T3 fibroblasts exposed to 1 mM 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH) | Reduced ROS production | [77] |
Poaceae |
Oryza sativa L. (rice) |
panicles | ethyl acetate (0.1 to 100 µg/mL) |
gallic, protocatechuic, chlorogenic, caffeic, syringic, p-coumaric, ferulic, sinapic and rosmarinic acids, vanillin, and quercetin | HDFs exposed to 150 µmol/L H2O2 | Reduced oxidative stress | [78] |
Rosaceae |
Pourthiaea villosa (Thunb.) Decne. (oriental photinia) |
leaves | ethanolic (25 to 100 µg/mL) |
p-coumaric acid, caffeic acid, chlorogenic acid, patuletin, catechin, epicatechin, eriodictyol, naringenin, quercetin, and quercetin derivatives |
HDFs exposed to 1 mmol/L H2O2 | Reduced ROS production | [79] |
Salicaceae |
Populus nigra L. (Lombardy poplar) |
whole plant | aqueous (25 to 200 μg/mL) |
caffeic and p-coumaric acids | HDFs exposed to 100 µmol/L AAPH | Reduced ROS production | [80] |