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. 2021 May 5;10(5):726. doi: 10.3390/antiox10050726

Table 1.

Selected plant extracts from different species with identified phenolic compounds and their in vitro effect on dermal fibroblast cells and ROS production.

Name of the Families Name of the Species
(Common Names)
Part of the Plant Type of Extract
(Concentrations)
Identified Bioactive Cell Lines Mechanisms of Action Ref.
Annonaceae Annona muricata L.
(soursop)
leaves aqueous
(12.5 to 200 µg/mL)
quercetin 3-glucoside, rutin, chlorogenic acid, catechin, and gallic acid L929 fibroblasts exposed to 750 µmol/L H2O2 Reduced ROS production [76]
Onagraceae Fuchsia magellanica
Lam.
(hardy fuchsia)
leaves aqueous/ethanolic
(1000 µg/mL)
various phenolic acid,
flavonoid, and anthocyanin derivatives
3T3 fibroblasts exposed to 1 mM 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH) Reduced ROS production [77]
Poaceae Oryza sativa L.
(rice)
panicles ethyl acetate
(0.1 to 100 µg/mL)
gallic, protocatechuic, chlorogenic, caffeic, syringic, p-coumaric, ferulic, sinapic and rosmarinic acids, vanillin, and quercetin HDFs exposed to 150 µmol/L H2O2 Reduced oxidative stress [78]
Rosaceae Pourthiaea villosa (Thunb.) Decne.
(oriental photinia)
leaves ethanolic
(25 to 100 µg/mL)
p-coumaric acid, caffeic acid, chlorogenic acid,
patuletin, catechin, epicatechin, eriodictyol, naringenin, quercetin, and quercetin derivatives
HDFs exposed to 1 mmol/L H2O2 Reduced ROS production [79]
Salicaceae Populus nigra L.
(Lombardy poplar)
whole plant aqueous
(25 to 200 μg/mL)
caffeic and p-coumaric acids HDFs exposed to 100 µmol/L AAPH Reduced ROS production [80]