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. 2021 May 4;9(5):458. doi: 10.3390/vaccines9050458

Figure 1.

Figure 1

BEI-iSs160 vaccine induces specific humoral immunity. Specific anti-NNV IgM levels in the serum of Senegalese sole specimens 7-, 15- and 30-days after intraperitoneal vaccination with low and high dosages (105 and 107 TCID50/mL, iSs160L and iSs160H, respectively) of BEI-iSs160 vaccine (inactivated with BEI) and form-iSs160 (formalin inactivated) or PBS (Control). Data represent the mean ± standard error of the mean (SEM; n = 6 fish/group and time point). Lower letters denote statistical differences between groups at a same time-point (p < 0.05), whilst asterisks indicate those between time-points in the same group (* p < 0.05; **** p < 0.0001).