. Author manuscript; available in PMC: 2021 Jul 4.
Published in final edited form as: Nat Genet. 2021 Jan 4;53(1):65–75. doi: 10.1038/s41588-020-00748-0
Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms