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. Author manuscript; available in PMC: 2021 Jul 4.
Published in final edited form as: Nat Genet. 2021 Jan 4;53(1):65–75. doi: 10.1038/s41588-020-00748-0

Table 1.

Baseline Characteristics of the Participants.

Multiancestry GWAS Sample Population Group Replication Sample Population Group

Total European African East Asian Hispanic European
(UK Biobank)
African
(AFR CA UG)
Cases Controls Cases Controls Cases Controls Cases Controls Cases Controls Cases Controls Cases Controls
No. of participants 107,247 127,006 85,554 91,972 10,368 10,986 8,611 18,809 2,714 5,239 6,852 193,117 1,586 1,047
No. with individual level data a 84,574 65,134 71,570 52,531 9,126 8,702 1,652 1,803 2,226 2,098 6,852 193,117 1,586 1,047
No. ≤ 55 years of age 8,959 13,562 7,099 11,471 1,628 1848 47 81 185 162 481 79,347 354 277
No. with aggressive disease b 26,374 - 21,917 - 2,934 - 753 - 770 - - - - -
a

These participants are also included in GRS and stratified analyses.

b

Aggressive disease defined as stage T3/T4, regional lymph node involvement (N1), metastatic disease (M1), a tumor with a Gleason Score ≥ 8, or a prostate-specific antigen (PSA) level ≥ 20 ng/mL, or, prostate cancer as the underlying cause of death.