TABLE 1.

Overview of the main known functions of Semaphorins in the adult brain.

Semaphorin	Function	References
Sema3A	Restriction of visual cortex plasticity Inhibition of SVZ neurogenesis Specific re-innervation of bitter taste receptor cells Control of axon growth of GnRH neurons Affecting the rigidity of PNN	Boggio et al. (2019) Sun et al. (2016) Lee et al. (2017) Giacobini et al. (2014) Djerbal et al. (2019)
Sema3F	Homeostatic synaptic plasticity Hippocampal synaptic transmission Npn-2: maintenance and function of corticostriatal circuitry	Wang et al. (2017) Sahay et al. (2005) Assous et al. (2019)
Sema3G	Maintenance of hippocampal synaptic connectivity and retention of fear memories	Tan et al. (2019)
Sema4C	Maintenance of hippocampal synaptic connectivity and retention of fear memories	Simonetti et al. (2019)
Sema5A	Control of maturation of adult-born hippocampal granule cells	Duan et al. (2014)
Sema7A	Inhibition of hippocampal neurogenesis Specific re-innervation of sweet taste receptor cells Control of GnRH release in the pituitary circulation	Jongbloets et al. (2017) Lee et al. (2017) Parkash et al. (2015)

GnRH, gonadotropin releasing hormone; SVZ, subventricular zone.