Skip to main content
. 2020 Dec 15;11(5):1200–1212. doi: 10.1016/j.apsb.2020.12.008

Figure 1.

Figure 1

Celastrol (Cel) reduces body weight of high fat diet (HFD)-induced metabolic syndrome (MetS) mice. (A) The chemical structure of celastrol. (B)–(D) Analysis of mice on HFD, either without (HFD, n = 7) or treated with celastrol at doses of 0.75 mg/kg/day (HFD+Cel 0.75, n = 7), 1 mg/kg/day (HFD+Cel 1.5, n = 7), or 3 mg/kg/day (HFD+Cel 3, n = 7), including: (B) phenotypic presentation; (C) body weight; (D) food intake (n = 4). Data represent as mean ± standard error of mean (SEM) in (C) (n = 7) and (D) (n = 4). P values are determined by two-tailed Student's t test. ∗P < 0.05, ∗∗P < 0.01.