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. 2021 May 6;11(5):1325. doi: 10.3390/ani11051325

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Overview of DNA methylation results of single CpGs for the selected genes. DNA methylation (DNMT1, DNMT3A, DNMT3B), embryo-maternal recognition (ESR1, CYP19A1, PTGES2), and growth and development (NANOG, SOX2) of the equine embryo. Blue box, unmethylated CpG; red box, methylated CpG; gray box, unclear methylation state. One row refers to one embryo and the number of columns refers to the number of CpGs sequenced in the CG-rich region (methprimer CpG island finder) upstream of the gene (Table 2).