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. 2021 May 6;11(5):379. doi: 10.3390/jpm11050379

Table 1.

Inclusion and exclusion criteria.

Inclusion Criteria Exclusion Criteria
Age from 30 to 65 years Age under 30 and over 65 years
Mild form of respiratory SARS-CoV-2 disease Severe or critical form of SARS-CoV-2 pulmonary infection
Non-specific neurological symptoms such as smell and taste dysfunction, vertigo, headache, dizziness or fatigue Disturbance in consciousness, acute cerebrovascular disease (ischemic stroke, cerebral hemorrhage, subarachnoid hemorrhage), acute encephalopathy, encephalitis or meningitis, polyneuropathy, demyelinating spectrum of disease and seizures.
SARS-CoV infection from 30 to 60 days before TCCD recording More than 60 days from infection start and TCCD recording
Treated exclusively with supportive therapy Use of antibiotics, corticosteroids, oxygen for SARS-CoV-2 infection
Diagnosis confirmed by a positive result of real-time reverse PCR test by nasal/pharyngeal swabs History of uncontrolled hypertension, nonregulated diabetes mellitus, cerebrovascular disease, hematologic disease, atrial fibrillation, chronic heart disease or cancer
Severe alcohol consumption (more than 10 drinks per week)
Stenosis of extracranial vertebrobasilar artery > 20%
Stenosis of extracranial carotid artery > 20%.
For control group negative real time reverese PCR test by nasal/pharyngeal swabs Negative serological IgM and IgG test on SARS-CoV-2 virus Known occlusive disease of intracranial cerebral arteries
No SARS-CoV-2 symptoms at all Using anticoagulant drug, vasodilatory drugs, hormone replacement therapy, β-blocking agents, calcium channel blockers