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. 2021 May 5;13(5):661. doi: 10.3390/pharmaceutics13050661

Figure 1.

Figure 1

Structure of keratin 1 targeting peptide-Dox conjugate (PDC). The conjugate contains an N-acyl hydrazone linker which hydrolyzes under aqueous acidic conditions to give unmodified doxorubicin (Dox) and hydrazide linker with the peptide. Peptide, linker, and Dox are shown in red, blue, and black, respectively.