Clinical signs monitored after challenge. The individual clinical signs were recorded after CSFV “Margarita” strain infection. Animals 2 to 7 (group A) and 14 to 18 (group C) were challenged after 21 and 5 dpv, respectively. Animals 8 to 11 (group B), contacts for group A and 19 to 23 (group D), infection control group, were not vaccinated but challenged. Pigs were monitored daily for clinical signs during the 13 dpc or until euthanasia. Different shades of colour and the numerical clinical score represent the severity of the clinical signs as shown in the legend. Super-indexed letters in the mean clinical score value from each group are employed to represent statistically significant differences between the groups on that day; similar letters indicate no statistical difference, and different letters show statistical difference (p < 0.05).