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. 2021 May 6;9(5):518. doi: 10.3390/biomedicines9050518

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Hepatic inflammation-related gene expression: HFC and chow diets. Hepatic gene expression of inflammatory markers (A) Tnf-α, (B) Cd68, (C) Ccl2, (D) Il12, (E) Caspase1, (F) Ctsd, (G) Icam and (H) Vcam. n = 6–8 mice per group for gene expression analyses. All error bars represent standard error of the mean. Statistical significance is indicated as follows: Npc1^nih-tp mice on a HFC or chow diet vs. Npc1^wt-tp mice on a HFC or chow diet (# p ≤ 0.05; ## p < 0.01; #### p < 0.0001); Npc1^wt-tp or Npc1^nih-tp on a HFC or chow diet vs. Npc1^wt-tp or Npc1^nih-tp mice on a plant stanol-enriched HFC or chow diet (* p ≤ 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001).