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. 2021 May 25;16(5):e0251048. doi: 10.1371/journal.pone.0251048

Table 2. Overall description of comorbidities, medication usage and general complications.

Variables non-AKI group CoV-AKI group p Value
(n = 80) (n = 198)
Hospitalization ICU (%) 30 (37.5%) 138 (69.7%) <0.001*
Comorbidities (%)
Hypertension
    No 46.1 29.5 0.010*
    Yes 53.9 70.5
Type 2 Diabetes
    No 67.1 58.4 0.190
    Yes 32.9 41.6
Smoking
    No 76.3 66.8 0.129
    Yes 23.7 33.2
Obesity
    No 85.5 83.2 0.635
    Yes 14.5 16.8
Chronic Respiratory Disease
    No 85.5 83.7 0.758
    Yes 14.5 16.3
Cardiopathy
    No 81.6 77.9 0.506
    Yes 18.4 22.1
Hepatic Diseases
    No 98.7 93.6 0.085
    Yes 1.3 6.4
Previous AKI
    No 92.1 85.3 0.135
    Yes 7.9 14.7
Medication Use (%)
Hydroxychloroquine
    No 93.8 98.0 0.071
    Yes 6.2 2.0
Azithromycin
    No 73.8 78.3 0.416
    Yes 26.2 21.7
Hydroxycloroquine+Azithromycin
    No 68.8 49.5 0.003*
    Yes 31.2 50.5
Vasopressor agents
    No 93.7 50.9 <0.001*
    Yes 6.3 49.1
Complications (%)
Sepsis
    No 38.8 45.5 0.759
    Yes 61.3 54.5
SOFA Score
    0–6 83.7 65.4
    7–9 8.2 18.7 0.123
    10–12 8.2 9.3
    13–14 0 5.6
    15 0 0.9
    15–24 0 0
Mechanical Ventilation
    No 85.4 44.5 < 0.001*
    Yes 14.6 55.5

Description of comorbidities, medication usage and general complications between COVID-19 AKI patients and COVID-19 non-AKI patients. SOFA: Sequential Organ Failure Assessment. Data were expressed as percentage and analyzed using Chi-Square test. (*p<0.05).