Table 3. Logistic regression analyses of factors associated with AKI in COVID-19-positive patients.
| Univariate Logistic Model | Multivariate Logistic Model | |||
|---|---|---|---|---|
| OR (95% CI) | P Value | OR (95% CI) | P Value | |
| Male Sex (no/yes) | 1.91 (0.69–2.05) | 0.530 | ||
| Age (>62 years) | 1.68 (0.99–2.83) | 0.050* | ||
| Hypertension (no/yes) | 2.04 (1.18–3.54) | 0.001* | 2.62 (1.21–5.67) | 0.015 |
| Type 2 Diabetes (no/yes) | 1.45 (0.83–2.53) | 0.191 | ||
| Smoking (no/yes) | 1.59 (0.87–2.94) | 0.131 | ||
| Obesity (no/yes) | 1.20 (0.57–2.52) | 0.636 | ||
| Respiratory Disease (no/yes) | 1.16 (0.55–2.45) | 0.698 | ||
| Cardiopathy (no/yes) | 1.26 (0.64–2.47) | 0.506 | ||
| Hepatic Diseases (no/yes) | 5.11 (0.65–40.0) | 0.220 | ||
| Previous AKI (no/yes) | 2.00 (0.79–5.06) | 0.141 | ||
| CRP (>187.5 mg/L) | 2.44 (1.41–4.22) | 0.001* | ||
| D-dimer (> 1.77 μg/L) | 1.21 (0.69–2.14) | 0.502 | ||
| Hemoglobin (>13.5 g/dL) | 0.94 (0.56–1.58) | 0.822 | ||
| Hematocrit (> 39.7%) | 0.76 (0.45–1.29) | 0.308 | ||
| MCV (> 90.3 fL) | 1.80 (1.06–3.05) | 0.029* | ||
| MCH (> 30.5 pg) | 1.59 (0.94–2.69) | 0.082 | ||
| RDW (> 13.6%) | 0.92 (0.55–1.55) | 0.763 | ||
| MCHC (> 33.8 g/dL) | 1.27 (0.75–2.13) | 0.377 | ||
| Leukocyte (> 8590 cell/μL) | 2.16 (1.26–3.70) | 0.005* | ||
| Neutrophil (> 6662 cell/μL) | 2.22 (1.30–3.80) | 0.003* | ||
| Eosinophil (> 0 cell/μL) | 1.19 (0.70–1.99) | 0.522 | ||
| Basophil (> 10 cell/μL) | 0.92 (0.55–1.55) | 0.763 | ||
| Lymphocyte (> 1048 cell/μL) | 0.76 (0.45–1.27) | 0.290 | ||
| Monocyte (> 466 cell/μL) | 1.25 (0.74–2.10) | 0.405 | ||
| Platelet (> 1.9x106/μL) | 1.07 (0.64–1.80) | 0.791 | ||
| NLR (> 6.4) | 2.24 (1.31–3.83) | 0.003* | ||
| PLR (> 175.9) | 1.02 (0.60–1.68) | 0.989 | ||
| Hydroxychloroquine use (no/yes) | 3.23 (0.85–12.37) | 0.286 | ||
| Azithromycin use (no/yes) | 0.78 (0.43–1.43) | 0.417 | ||
| Hydroxychloroquine+Azithromycin use (no/yes) | 2.25 (1.29–3.89) | 0.004* | ||
| Mechanical Ventilation (no/yes) | 7.29 (3.01–17.67) | 0.001* | ||
| Vasoactive Drug (no/yes) | 14.46 (4.24–49.34) | <0.001 | 14.36 (4.14–49.8) | <0.001 |
Data are reported as odds ratio (OR) and 95% Confidence Interval (95% CI). All variables showing a p<0.20 in the univariate analysis were presented to the multivariate models by using the forward method. Variables were retained in the model if a Wald test revealed.