TABLE 4.

Integrated pipelines used to infer microbe-host interactions by combining heterogeneous -omic datasets.

Methodology	Functionalities
MicrobioLink (Andrighetti et al., 2020)	Integrating microbe-host protein interaction networks with host responses and host regulatory/signaling networks using network diffusion principles
KBase (Arkin et al., 2018)	Integrated platform enabling data sharing, integration, and analysis of -omic datasets from microbes, plants, and their communities by creating computational workflows
Li et al. (2015a)	Identifying critical effectors involved in host-pathogen interactions by integrating multiple lines of -omic evidence