Skip to main content
. 2021 Apr 26;13(9):12607–12630. doi: 10.18632/aging.202937

Table 2. Differentially expressed genes with high degrees of connectivity (node degrees ≥ 5).

Number Gene type Gene name Genbank description Node degrees
1 miRNA hsa-miR-15a-5p NA 876
2 mRNA ATP6V1A ATPase H+ transporting V1 subunit A 87
3 mRNA CCT8 Chaperonin containing TCP1 subunit 8 72
4 mRNA BCL2L11 BCL2-like 11 66
5 mRNA AJUBA Ajuba LIM protein 45
6 mRNA MAN2B1 Mannosidase alpha class 2B member 1 42
7 mRNA HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 32
8 mRNA SP1 Sp1 transcription factor 28
9 mRNA MIA3 MIA SH3 domain ER export factor 3 21
10 mRNA DVL2 Disheveled segment polarity protein 2 19
11 miRNA hsa-miR-381-3p NA 18
12 miRNA hsa-miR-3187-3p NA 12
13 mRNA RNF138 Ring finger protein 138 10
14 circRNA hsa_circ_0026129 NA 8
15 mRNA LMO7 LIM domain 7 8
16 miRNA hsa-miR-199b-5p NA 8
17 circRNA hsa_circ_0039463 NA 7
18 miRNA hsa-miR-20a-5p NA 6
19 circRNA hsa_circ_0055307 NA 6
20 circRNA hsa_circ_0041084 NA 6
21 circRNA hsa_circ_0041087 NA 6
22 circRNA hsa_circ_0002507 NA 6
23 circRNA hsa_circ_0026483 NA 6
24 circRNA hsa_circ_0008706 NA 6
25 circRNA hsa_circ_0026490 NA 6
26 miRNA hsa-miR-151a-3p NA 6
27 mRNA SEC24A SEC24 homolog A, COPII coat complex component 6
28 circRNA hsa_circ_0063132 NA 5
29 mRNA ESR2 Estrogen receptor 2 5
30 circRNA hsa_circ_0026486 NA 5
31 circRNA hsa_circ_0060098 NA 5
32 mRNA IRS2 Insulin receptor substrate 2 5
33 circRNA hsa_circ_0026491 NA 5
34 circRNA hsa_circ_0026484 NA 5
35 circRNA hsa_circ_0026482 NA 5
36 mRNA TNC Tenascin C 5