Table 3.
A comparison of hydrophobic interactions in the VEGF-A/VEGFR-2 and VGB1/VEGFR-2
| Receptor | Ligand | ||
|---|---|---|---|
| VEGF-A/VEGFR-2 Complex | VGB1/VEGFR-2 Complex | VEGF-A/VEGFR-2 Complex | VGB1/VEGFR-2 Complex |
| Tyr165 | His133 | #Phe17 | Cys1 |
| Met197 | Val135 | $Met18 | Ser2 |
| Ile215 | Arg164 | *Tyr21 | #Trp3 |
| Tyr165 | Gln22 | $Ile4 | |
| Gly196 | ¤Tyr25 | Asp5 | |
| Met197 | Val6 | ||
| Met213 | *Tyr7 | ||
| Ile215 | Ala10 | ||
| Val254 | ¤Thr11 | ||
| Gly255 | Pro14 | ||
| Asp257 | Arg15 | ||
| Glu284 | Leu17 | ||
| Lys286 | |||
| Ser311 | |||
| Gly312 | |||
#, $, *, ¤ These symbols show corresponding residues in VEGF-A and VGB1.