Para-axial T1-weighted spin-echo MR images.
A, Five minutes after the first intravenous administration of an SD (0.1 mmol/kg) of the paramagnetic contrast agent, no contrast enhancement attributable to a white matter lesions is visible.
B, Five minutes after the administration of a second SD of the paramagnetic contrast agent (for a total of 0.2 mmol/kg), no contrast enhancement attributable to a white matter lesion is detectable.
C, Five minutes after the administration of a third SD of the paramagnetic contrast agent (for a total of 0.3 mmol/kg), a small area of contrast enhancement is clearly visible in the right hemisphere (arrow).