TABLE 1:
Individual MR imaging signs of tumor recurrence versus radiation necrosis results
| Corpus Callosum | Midline Spread | Subependymal Spread | Multiple Lesions | Spreading Wavefront | Septum Pellucidum | Pathologic Diagnosis | |
|---|---|---|---|---|---|---|---|
| Totals | |||||||
| Presence | 4 | 1 | 6 | 3 | 6 | 4 | Necrosis |
| Absence | 8 | 11 | 6 | 9 | 6 | 8 | Necrosis |
| Presence | 10 | 2 | 11 | 9 | 3 | 2 | Tumor |
| Absence | 5 | 13 | 4 | 6 | 12 | 13 | Tumor |
| P value* | .12 | 1 | .26 | .12 | .13 | .36 | |
| Sign favors diagnosis of: | Tumor | Neither | Tumor | Tumor | Necrosis | Necrosis | |
| Sensitivity (%) | 66.7 | N/A | 73.3 | 60 | 50 | 33.3 | |
| Specificity (%) | 66.7 | N/A | 50 | 75 | 81.3 | 86.7 | |
| Positive predictive value (%) | 71.4 | N/A | 64.7 | 75 | 66.7 | 66.7 | |
| Negative predictive value (%) | 61.5 | N/A | 60 | 60 | 68.4 | 61.9 | |
| Accuracy (%) | 66.7 | N/A | 63 | 67 | 68 | 63 |
*
Fisher’s exact 2-tailed test.