Table 2.
MPN PRO use in clinical trials by therapy
| Trial Name | MPN | PRO | |
|---|---|---|---|
| Ruxolitinib | COMFORT 1 | Myelofibrosis | MF-SAF 2.0 |
| COMFORT 2 | Myelofibrosis | FACT-LYM | |
| RETHINK | Myelofibrosis | MPN-10 | |
| RESPONSE | Polycythemia vera | MPN-SAF | |
| RELIEF | Polycythemia vera | MPN-SAF | |
| MAGIC | Essential thrombocythemia | MPN-SAF | |
| Fedratinib | JAKARTA | Myelofibrosis | MF-SAF |
| Pacritinib | PERSIST 1&2 | Myelofibrosis | MPN-SAF |
| Momelotinib | SIMPLIFY 1&2 | Myelofibrosis | MPN-SAF |
| Pomalidomide | RESUME | Myelofibrosis | FACT-AN |
| PEG INFa2a | MPD-RC112 | Myelofibrosis | MPN-SAF |
| MPD-RC112 | Essential thrombocythemia | MPN-SAF |
FACT-LYM Functional Assessment of Cancer Therapy in Lymphoma, MF-SAF Myelofibrosis Symptom Assessment Form, MPN-SAF Myeloproliferative Neoplasm Symptom Assessment Form, PEG INFa2a pegylated-interferon alpha-2a