Table 2.
Abnormal Laboratory Tests and Polycythemia Vera—Related Signs and Symptoms at Time of Diagnosis in 2510 Patients
| Characteristic | Value |
|---|---|
| Abnormal Laboratory Testa | |
| Hemoglobin | 1482 (59.0) |
| Hematocrit | 1443 (57.5) |
| Platelet count | 720 (28.7) |
| White blood cell count | 499 (19.9) |
| Erythropoietin level | 505 (20.1) |
| Red blood cell count | 454 (18.1) |
| Red cell mass | 105 (4.2) |
| Serum LDH | 88 (3.5) |
| EEC growth | 8 (0.3) |
| Palpable splenomegaly | 175 (7.0) |
| Mutational Test | 1236 (49.2) |
| JAK2 V617F, n/N (%)b | 1184/1236 (95.8) |
| JAK2 other, n/N (%)b | 10/1236 (0.8) |
| Missing, n/N (%)b | 42/1236 (3.4) |
| Bone marrow test | 612 (24.4) |
| Symptoms (Documented by Physician) | |
| Tiredness | 552 (22.0) |
| Itching | 349 (13.9) |
| Muscle aches and/or bone pain | 220 (8.8) |
| Difficulty sleeping | 195 (7.8) |
Data are presented as n (%) unless otherwise indicated.
Abbreviations: EEC = endogenous erythroid colony; JAK2 = Janus kinase 2; LDH = lactate dehydrogenase.
a
As reported by survey respondents; definitions of “abnormal” were not available. A patient could be counted in > 1 category.
b
Denominator of 1236 is number of patients who had mutational analysis data from peripheral blood test or other test.