TABLE 1:
Mean and standard deviation of each perfusion measure in lesions and normal-appearing white matter in patients with multiple sclerosis compared with those of normal white matter in control subjects
| Lesion/Region | Cerebral Blood Flow | Cerebral Blood Volume | Mean Transit Time |
|---|---|---|---|
| Enhancing | 21.5 ± 5.1 | 1.4 ± 0.3 | 5.0 ± 1.4¶ |
| Nonenhancing: class 1 | 10.2 ± 1.8¶ | 0.8 ± 0.2£ | 6.3 ± 1.2¶ |
| Nonenhancing: class 2 | 20.9 ± 5.8 | 1.6 ± 0.5£ | 4.8 ± 0.7¶ |
| NAWM: contralateral to enhancing | 16.9 ± 3.7§ | 1.06 ± 0.3 | 5.0 ± 1.5¶ |
| NAWM: contralateral to class 1 | 16.1 ± 5.9§ | 1.09 ± 0.3 | 5.1 ± 1.0¶ |
| NAWM: contralateral to class 2 | 18.3 ± 6.9§ | 1.24 ± 0.3 | 4.6 ± 0.9¶ |
| Normal white matter (control group) | 28.3 ± 10.3 | 1.2 ± 0.5 | 1.3 ± 0.5 |
Enhancing indicates enhancing lesions; nonenhancing: class 1, nonenhancing lesions with decreased perfusion and perfusion measures dissimilar to those of enhancing lesions; nonenhancing: class 2, nonenhancing lesions with increased perfusion and perfusion measures similar to those of enhancing lesions; NAWM, normal appearing white matter. The Dunnett-Hsu corrected significance levels for the comparison of each lesion type and normal-appearing white matter to control normal white matter with respect to each perfusion measure are also reported here, and values of significance at the familywise levels are highlighted as
: P < .001,
: P ≤ .01,
: P < .05.