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Half-Lives of Potential Long-Acting Drugs
| median terminal half-lives | ref | |
|---|---|---|
| rilpivirine (RPV) | 50 h | 302 |
| https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/202022s008lbledt.pdf | ||
| tenofovir alafenamide (TAF) | 92 min* | *in dogs |
| 119 | ||
| TFV-DP (active metabolite of TAF) | 50−180 h | 303,304 |
| https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/207561s002lbl.pdf | ||
| islatravir (EFdA) | 78.5−128 h | 299 |
