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. 2021 May 26;37(4):795–815. doi: 10.1016/j.ccc.2021.05.005

Table 2.

The Berlin definition for clinical diagnosis of acute respiratory distress syndrome

Variable Criteria
Timing Within 1 wk of clinical insult or worsening respiratory symptoms
Chest imaginga Bilateral opacities not fully explained by effusion, collapse, or nodules
Origin of pulmonary edema Respiratory failure not fully explained by a cardiac cause or fluid overload
Oxygenation
Mild 200 mm Hg < Pao2/Fio2 ≤ 300 mm Hg with PEEP or CPAP ≥ 5 cm H2O
Moderate 100 mm Hg < Pao2/Fio2 ≤ 200 mm Hg with PEEP ≥ 5 cm H2O
Severe Pao2/Fio2 ≤ 100 mm Hg with PEEP ≥ 5 cm H2O

Abbreviations: PEEP, positive end-expiratory pressure; CPAP, continuous positive airway pressure.

a

Either chest radiograph or computed tomographic scans could be used for the imaging criteria.