Table 2.
Characteristics and outcomes of the 237 patients in the study cohort.
| All patients N = 237 | |
|---|---|
| Age—(year), mean ± SD | 45.0 ± 20.2 |
| Female sex—no. (%) | 60 (25.3) |
| Height—(cm), mean ± SD | 166.3 ± 9.7 |
| Weight—(kg), mean ± SD | 78.2 ± 19.6 |
| Body mass index—(kg/m2), mean ± SD | 28.3 ± 7.2 |
|
| |
| Chronic illnesses—no. (%) | |
| Diabetes | 75 (31.7) |
| Chronic respiratory disease | 27 (11.3) |
| Chronic cardiac disease | 23 (9.7) |
| Immunocompromised disorder | 6 (2.5) |
| Chronic renal disease | 6 (2.5) |
| Chronic liver disease | 11 (4.6) |
|
| |
| Admission category, no. (%) | |
| Medical | 112 47.3) |
| Surgical | 11 (4.6) |
| Nonoperative trauma | 114 (48.1) |
| Traumatic brain injury—no. (%) | 62 (26.2) |
| Sepsis on admission—no. (%) | 51 (21.5) |
| APACHE II—mean ± SD | 20.4 ± 8.1 |
| SOFA score day 1—mean ± SD | 10.0 ± 2.8 |
| Vasopressor use—no. (%) | 135 (57.0) |
| Mechanical ventilation—no. (%) | 234 (98.7) |
|
| |
| Intervention group—no. (%) | |
| Standard feeding | 120 (50.6) |
| Permissive underfeeding | 117 (49.4) |
| Total caloric intake (kcal/day)—mean ± SD | 1143.6 ± 466.1 |
| Total protein intake—(g/day) mean ± SD | 55.9 ± 21.0 |
|
| |
| Laboratory tests | |
| Inclusion blood glucose—(mmol/L), mean ± SD | 9.0 4.1 |
| Creatinine—(µmol/L), mean ± SD | 100.8 ± 93.9 |
| Bilirubin—(µmol/L), mean ± SD | 25.4 ± 39.2 |
| Platelets—(109/L), mean ± SD | 214 ± 128 |
| Albumin—(g/L), mean ± SD | 28.8 ± 5.6 |
|
| |
| Outcomes | |
| Mechanical ventilation duration—(days), mean ± SD | 13.0 ± 25.0 |
| ICU LOS—(days), mean ± SD | 15.9 ± 10.5 |
| Hospital LOS—(days), mean ± SD | 59.3 ± 83.1 |
| 90-day mortality | 61 (25.7) |
| ICU mortality—no. (%) | 38 (16.0) |
| Hospital mortality—no. (%) | 56 (23.6) |
| ICU-acquired infections—no. (%) | 96 (40.5) |
SD: standard deviation; APACHE: acute physiology and chronic health evaluation; SOFA: sequential organ failure assessment; ICU: intensive care unit; LOS: length of stay.