Skip to main content
. 2020 Dec 15;26(4):881–890. doi: 10.1007/s10741-020-10063-9

Table 1.

Imaging techniques to assess myocardial inflammation and its consequences in patients receiving anthracyclines (ANTs)

Acute/chronic phase, roles of imaging Imaging technique Main findings in ANT cardiotoxicity

Acute phase:

- Early detection of cardiac damage

- Prognostic stratification

(2D/3D) TTE LV/RV regional/global systolic dysfunction; diastolic dysfunction
(2D/3D) strain TTE Subclinical LV/RV systolic dysfunction
CMR LV/RV regional/global systolic dysfunction; LV/RV hyperintensity in T2w sequences; LGE; increase in regional/global T1 and T2 mapping values
SPECT LVEF decrease
18F-FDG PET Increased glucose uptake

Chronic phase:

- Detection of cardiac damage

- Follow-up of known cardiomyopathy

TTE LV/RV regional/global systolic dysfunction; diastolic dysfunction
CMR LV/RV regional/global systolic dysfunction; LGE
SPECT LVEF decrease

2D/3D two-/three-dimensional, 18F-FDG PET, 18F-fluoro-D-glucose positron emission tomography, CMR cardiac magnetic resonance, LGE late gadolinium enhancement, LV/RV left/right ventricle, TTE transthoracic echocardiography