Table 1.
Acute/chronic phase, roles of imaging | Imaging technique | Main findings in ANT cardiotoxicity |
---|---|---|
Acute phase: - Early detection of cardiac damage - Prognostic stratification |
(2D/3D) TTE | LV/RV regional/global systolic dysfunction; diastolic dysfunction |
(2D/3D) strain TTE | Subclinical LV/RV systolic dysfunction | |
CMR | LV/RV regional/global systolic dysfunction; LV/RV hyperintensity in T2w sequences; LGE; increase in regional/global T1 and T2 mapping values | |
SPECT | LVEF decrease | |
18F-FDG PET | Increased glucose uptake | |
Chronic phase: - Detection of cardiac damage - Follow-up of known cardiomyopathy |
TTE | LV/RV regional/global systolic dysfunction; diastolic dysfunction |
CMR | LV/RV regional/global systolic dysfunction; LGE | |
SPECT | LVEF decrease |
2D/3D two-/three-dimensional, 18F-FDG PET, 18F-fluoro-D-glucose positron emission tomography, CMR cardiac magnetic resonance, LGE late gadolinium enhancement, LV/RV left/right ventricle, TTE transthoracic echocardiography