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. 2021 May 18;2(5):100276. doi: 10.1016/j.xcrm.2021.100276

Figure 1.

Figure 1

The frequencies of germline predisposing variants and somatic driver mutations of DNA damage repair genes in 9,738 non-hypermutator TCGA cases

(A) The frequencies of samples carrying germline predisposing variants or somatic driver mutations in 80 core DDR genes.

(B) Percentage of cases with germline predisposing variants in DDR pathways.

(C) Percentage of cases with somatic driver mutations in DDR pathways.

(D) Comparison of the total numbers of germline predisposing variants and somatic driver mutations in DDR genes across 9,738 non-hypermutator TCGA cases. Colors represent different DDR pathways.