Table 1.

Body weight and glucose of the experimental animals.

	Wild-type mice		Casp-11−/− mice
	Normal diet	HFD/STZ	Normal diet	HFD/STZ
Body weight (g)	28.8 ± 5.2	22.4 ± 4.8*	29.3 ± 3.6	24.2 ± 3.3*
Glucose (mmol/L)	6.6 ± 0.7	24.6 ± 5.9*	6.9 ± 0.5	25.9 ± 4.6*

Mice were fed a HFD for 4 weeks and then injected with 3 consecutive days of STZ (intraperitoneal at 70 mg/kg) followed by continued HFD feeding for an additional 12 weeks. Values are means ± SEM (n = 6).

HFD high-fat diet, STZ streptozotocin.

*P < 0.05 versus normal-diet mice.