Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 25;7:36. doi: 10.1038/s41421-021-00271-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — a Clinical characteristic of 17 PDAC patients with abundant meCAFs included in our study. b Response evaluation of the 17 PDAC patients receiving 6 cycles of chemotherapy (gemcitabine plus albumin-bound paclitaxel) combined with PD-1 antibody (10 partial responses, 1 complete response, objective response rate: 64.71%). c The response of a representative loose-type PDAC patient after receiving chemotherapy combined with PD-1 antibody treatment and PD-1 antibody alone. H&E and IHC stainings of PLA2G2A and PD-L1 were examined. Follow-up clinical indicators including MRI and serum CA-199 after treatment are shown. CR, complete response; AG, gemcitabine plus albumin-bound paclitaxel; ULN, upper limit of normal. d Schematic diagram summarizing the intertumoral heterogeneity of cellular components, function and metabolism in dense- and loose-type PDACs, suggesting potential clinical significance and therapeutic strategies.