Table 1.

Elements of haemodialysis (HD) prescription and pharmacological therapy according to treatment allocation

Parameter	Incremental HD	Standard HD
HD frequency	Twice-weekly for 6 weeks followed by thrice-weekly	Thrice-weekly
HD duration per session	4 hours in the first 6 weeks, then as directed by patient’s nephrologist	Directed by patient’s nephrologist
Adjuvant pharmacological therapy	Loop diuretic±thiazide diuretic Patiromer Sodium bicarbonate	Directed by patient’s nephrologist
Dialysate bath	Potassium 3 mEq/L, calcium 2.5 mEq/L. Concentrations are adjusted by patient’s nephrologist as clinically indicated
Blood flow	According to standard of care
Dialysate flow	1.5 times blood flow rate
Volume removal	Ultrafiltration rate <13 mL/kg/hour
Other	Local practice and standard of care will be followed for anticoagulation, management of secondary hyperparathyroidism, management of hyperphosphataemia and management of iron deficiency and anaemia.