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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Am J Obstet Gynecol. 2020 Nov 26;225(1):85.e1–85.e11. doi: 10.1016/j.ajog.2020.11.035

Figure 2. Pharmacokinetic data.

Figure 2.

2a. Observed mean (symbols) and population mean (lines) TXA concentration-time profiles after 5 mg/kg, 10 mg/kg and 15 mg/kg IV doses derived from 30 patients. Doses are normalized to a 70 kg patient and shown on log scale. Error bars (1SD) are also shown. 2b. Actual measured TXA concentrations for each dose cohort for up to 2 hours and target pharmacokinetic concentration of 10 μg/mL for reference. All patients maintain over the 10 μg/mL threshold for at least 1 hour after administration.