Vascular inflammation is associated with skin disease severity in psoriasis.
Tomographic fused 18-FDG PET/ CT image of the aortic arch from a patient with severe skin disease and control patient (A). Regression plots for multivariable regression analysis of vascular inflammation as measured by target-to-background (TBR) with skin disease severity as measured by psoriasis area and severity (PASI) score. CI indicates confidence interval; and FRS indicates Framingham risk score.
The median TBR was 1.6±0.1 for controls and 1.8±0.3 (p<.001). CI indicates confidence interval; and FRS indicates Framingham risk score.
TBR: tissue- to- background ratio