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Cytotoxic (CC50), antiviral (IC50) activity, selectivity index (SI) of adamantyltetrazole derivatives 3а,b,d,e,h,i against the H1N1 influenza A virus strain
| Compound | CС50, μg/ml | IC50, μg/ml | SI |
|---|---|---|---|
| 3a | 46 ± 3 | 31 ± 4 | 1 |
| 3b | >300 | >300 | 1 |
| 3d | 4 ± 0.5 | 2 ± 0.3 | 2 |
| 3e | <3 | <3 | – |
| 3h | >167 | 15 ± 3 | 11 |
| 3i | 36 ± 2 | 15 ± 2 | 2 |
| Rimantadine | 60 ± 4 | 12 ± 2 | 5 |
