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. 2021 May 12;12:644855. doi: 10.3389/fmicb.2021.644855

TABLE 2.

The annotated PBP gene in Francisella species and subspecies using KEGG database.

Francisella tularensis subsp. tularensis Schu S4 Francisella tularensis subsp. holarctica LVS Francisella tularensis subsp. novicida U112
Locus (KEGG orthology) name [E.C. number], other information Locus (KEGG orthology) name [E.C. number], other information Locus (KEGG orthology) name [E.C. number], other information
Penicillin-binding protein 3 (PBP-3) FTT_0697 (K03587) FtsI Peptidoglycan D,D-transpeptidase, cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] ftsI; peptidoglycan synthetase FTL_1539 (K03587) cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] penicillin-binding protein (peptidoglycan synthetase) FTN_0607 (K03587) cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] ftsI; cell division protein, peptidoglycan synthetase (PBP)
PBP-4 FTT_1039 (K07259) serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] | dacB1; D-alanyl-D-alanine carboxypeptidase Uniprot Q5NG20 FTL_1046 (K07259) Serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] D-alanyl-D-alanine carboxypeptidase (Penicillin-binding protein) family protein FTN_0917 (K07259) Serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] serine-type D-Ala-D-Ala carboxypeptidase
PBP-4 No homolog found FTL_1509 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase FTN_0635 (K07259) serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] serine-type D-Ala-D-Ala carboxypeptidase
PBP-5/6 FTT_1029 (K07258) dacD, Serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] D-alanyl-D-alanine carboxypeptidase FTL_1060 (K07258) serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] | (GenBank) D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein) family protein FTN_0907 (K07258) serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
Penicillin-binding protein activator (LpoB) FTT_1540c (K07337) penicillin-binding protein activator hypothetical protein FTL_0571 (K07337) penicillin-binding protein activator, conserved hypothetical protein FTN_1449 (K07337) penicillin-binding protein activator, conserved protein of unknown function