FIGURE 1.

Protein level alteration of the reported Golgi structural proteins in various cancer types. Golgi reassembly-stacking proteins (GRASPs) (GRASP65 and GRASP55) and golgin families of proteins contribute to the structural scaffold that defines the Golgi architecture, and are conceived as the Golgi matrix. Altered protein levels of the Golgi matrix are discovered in different cancer types and may facilitate tumor progression. Upward red arrows indicate upregulated protein level, while downward arrows indicate down-regulated protein level of different matrix proteins in different cancer cells. Few studies are correlating the tethering conserved oligomeric Golgi (COG) complex with tumor metastasis, so a question mark is shown.