Table 1.
List of HITs as anti-fibrotic compounds.
| HIT compounds | Function |
|---|---|
| Irsogladine maleate | PDE4 inhibitor; antiulcer agent |
| Forskolin | Adenylyl cyclase activator |
| NKH 477 | Adenylyl cyclase activator |
| Pomiferin | PDE5 inhibitor |
| Retinoic acid | Endogenous retinoic acid receptor agonist |
| TTNPB | Retinoic acid analog; RAR agonist |
| AM 580 | Retinoic acid agonist |
| Tretinoin | All-trans retinoic acid |
| Tazarotene | Retinoic acid receptor alpha (RAR-α) |
| Rosiglitazone | Anti-diabetic medication |
| Ursocholanic acid | Cholesterol absorption |
| Pregnenolone succinate | NMDA receptor modulator |