Table 2.

Discounted and undiscounted base case and scenario analysis results, per-patient.

	DT				SOC
	ICERb	Cost	QALY	LY	Cost	QALY	LY
Discounted resultsa
Base case	$140,877	$2,372,482	26.4	29.9	$1,175,566	17.9	26.2
Females	$146,511	$2,377,583	26.8	30.3	$1,098,098	18.0	26.3
Males	$135,574	$2,367,928	26.1	29.5	$1,244,733	17.9	26.1
DT lasts 20-yearsc	$410,607	$2,761,601	21.8	27.2	$1,175,566	17.9	26.2
Females	$409,161	$2,703,690	22.0	27.4	$1,098,098	18.0	26.3
Males	$411,937	$2,813,307	21.7	27.0	$1,244,733	17.9	26.1
DT lasts 10-yearsc	$740,058	$2,914,175	20.3	26.5	$1,175,566	17.9	26.2
Females	$730,453	$2,836,566	20.4	26.7	$1,098,098	18.0	26.3
Males	$748,848	$2,983,469	20.2	26.4	$1,244,733	17.9	26.1
Undiscounted results
Base case	$15,332	$3,210,182	66.2	75.8	$2,770,348	37.6	54.9
Females	$24,825	$3,364,554	68.5	78.9	$2,607,231	38.0	55.6
Males	$5,778	$3,072,350	64.2	73.0	$2,915,988	37.2	54.3
DT lasts 20-yearsc	$162,116	$4,154,316	46.1	59.6	$2,770,348	37.6	54.9
Females	$163,939	$4,054,067	46.8	60.7	$2,607,231	38.0	55.6
Males	$160,380	$4,243,825	45.4	58.7	$2,915,988	37.2	54.3
DT lasts 10-yearsc	$419,576	$4,411,570	41.5	56.3	$2,770,348	37.6	54.9
Females	$411,772	$4,257,316	42.0	57.1	$2,607,231	38.0	55.6
Males	$426,872	$4,549,296	41.0	55.6	$2,915,988	37.2	54.3

DT durable therapy, SOC standard of care, ICER incremental cost-effectiveness ratio, QALY quality-adjusted life year, LY life year.

^aAll outcomes discounted at 3% per year.

^bICER units are 2018 US dollars per QALY.

^cExpected median duration.