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. 2020 Sep 16;42(6):861–870. doi: 10.1038/s41401-020-00521-3

Fig. 4. Effects of ketamine on dendritic spine maturation in MSNs.

Fig. 4

a Representative images and enlarged insets showing isolated dendritic branches from GABA- and TUJ1-positive neurons used to analyze dendritic spines. Scale bar = 10 μm. b–d Comparison of dendritic spine morphology in the vehicle group and the groups treated with various doses of ketamine or for 1 h (b), 8 h (c), and 24 h (d). Scale bar = 5 μm. Morphometric assessment of the number of dendritic spines observed in each group. The data are expressed as the mean ± SEM; *P < 0.05 vs. the vehicle group.